Background: Due to the limited number of clinical series and the lack of\nmulti-institutional or national registries concerning retroperitoneal sarcoma\n(RPS) extending to major arterio-venous structures, the short and long-term\nbenefits following concomitant resection of these major structures are still\nantagonistic. Objective: To present our institutional experience with RPS\ntumors, to assess their vascular involvement and to analyze the outcomes of\nonco-vascular approach. Patients and methods: A retrospective review of\nour institutional RPS patientsâ?? clinical charts was performed. All consecutive\nadult patients surgically treated for RPS were included. Resection of RPS tumors\nwas followed by histopathological examination for grading. Types of\nvascular involvement were assessed preoperatively. RPS tumors were resected\nen bloc together with blood vessels according to the type of vascular involvement\nand the surgical standards. Results: This study included 14 patients; 8\nmales (57%) and 6 females (43%) with RPS. Vascular resection was performed\nin all patients. Adherent structures were resected in 43%. Resection\nwas performed for 29% RPSs with arterial venous involvement, 14% with only\narterial involvement, and 57% with only venous involvement. All RPSs\nwere classified as high-grade lesions, and 64% showed secondarily major vessels\ninvolvement. 43% of patients were treated by arterial resection. 80% had\nvenous involvement. Venous resections were followed by venous reconstruction\nin all patients with both arterial and venous involvement. The morbidity\nrate was 43% while the mortality rate was 7%. Conclusion: Complete resection\nwith clear margins is important for long-term survival in patients with\nretroperitoneal soft tissue sarcomas.
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